Fast Palladium Catalyzed Arylation of Alkenes Using Bulky Monodentate Phosphorus Ligands
نویسندگان
چکیده
منابع مشابه
Novel monodentate spiro phosphorus ligands for rhodium-catalyzed hydrogenation reactions.
Novel monodentate phosphorus ligands containing the 1,1'-spirobiindane backbone have been synthesized and applied in the asymmetric rhodium-catalyzed hydrogenation of functionalized olefins, providing excellent enantioselectivities (up to 99.3% ee).
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A method for the Pd-catalyzed coupling of 2-aminothiazole derivatives with aryl bromides and triflates is described. Significantly, for this class of nucleophiles, the coupling exhibits a broad substrate scope and proceeds with a reasonable catalyst loading. Furthermore, an interesting effect of acetic acid as an additive is uncovered that facilitates catalyst activation.
متن کاملEfficient palladium-catalyzed N-arylation of indoles.
[equation--see text] The N-arylation of indoles, including a variety of substituted ones, has been carried out using bulky, electron-rich phosphines as the supporting ligand in combination with Pd(2)(dba)(3). Using this catalyst system, the efficient coupling of indole and a variety of substituted indoles with aryl iodides, bromides, chlorides, and triflates can be achieved.
متن کاملPalladium-Catalyzed α-Arylation of Aryl Nitromethanes
Catalytic conditions for the α-arylation of aryl nitromethanes have been discovered using parallel microscale experimentation, despite two prior reports of the lack of reactivity of these aryl nitromethane precursors. The method efficiently provides a variety of substituted, isolable diaryl nitromethanes. In addition, it is possible to sequentially append two different aryl groups to nitrometha...
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ژورنال
عنوان ژورنال: European Journal of Inorganic Chemistry
سال: 1999
ISSN: 1434-1948,1099-0682
DOI: 10.1002/(sici)1099-0682(199907)1999:7<1073::aid-ejic1073>3.0.co;2-t